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Search Results for " nogo-66 receptor "

3

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP1989L	Nogo-66 (1-40) aceate ( 475221-20-6 Free base)
	Nogo-66 (1-40) aceate (475221-20-6 Free base) 是对应于 Nogo-66 残基 1 - 40 的肽片段，Nogo-66 是抑制轴突生长的髓磷脂蛋白 Nogo 的结构域。Nogo-66 (1-40) aceate 作为 Nogo-66 受体 (NgR) 的竞争性拮抗剂，阻断 Nogo-66 和 CNS 髓磷脂诱导的轴突生长抑制，但不会减少髓磷脂相关糖蛋白 (MAG) 体外抑制神经突生长。Nogo-66 (1-40) aceate 促进体内脊髓损伤后半切脊髓轴突的再生和运动恢复。
TP1989	NEP(1-40) Nogo-66 (1-40)
	Peptide fragment corresponding to residues 1 - 40 of Nogo-66, the domain of the myelin protein Nogo that inhibits axonal outgrowth. Acts as a competitive antagonist at the Nogo-66 receptor (NgR); blocks Nogo-66- and CNS myelin-induced inhibition of axonal
T81685	NEP(1-40) TFA
	NEP(1-40) TFA 是一种Nogo-66 受体 (NgR) 的肽类拮抗剂，其作用机制为通过抑制髓蛋白所引发的损伤逆转，限制小胶质细胞形态分布的变化。

化合物

Nogo-66 (1-40) aceate ( 475221-20-6 Free base)

Cat.No: TP1989L

Cat.No: TP1989

Synonym: Nogo-66 (1-40)

Cat.No: T81685

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01200	Nogo Receptor/RTN4R Protein, Cynomolgus, Recombinant (His) NGR,NOGOR,RTN4R,NgR1,Nogo receptor	Cynomolgus	HEK293 Cells
	NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene.RTN4R may modulate the genetic risk or clinical expression of schizophrenia in a subset of patients and identify additional studies that will be necessary to clarify the role of RTN4R in psychiatric phenotypes.
TMPJ-00295	NgR Protein, Mouse, Recombinant (hFc) Nogo-66 Receptor,Nogo	Mouse	HEK293 Cells
	Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be prop...
TMPJ-00277	NgR3 Protein, Human, Recombinant (His) NGRL2,Nogo Receptor-Like 2,Reticulon-4	Human	HEK293 Cells
	Nogo-66 Receptor-Related Protein 3 (NgR3) has primary structures with NgR2 (NgRH1, NgRL3) and biochemical properties that are homologous to Nogo-66 receptor (NgR), and constitute a novel neuronal receptor protein family. NgR is GPI-anchored and contains eight leucine-rich repeats (LRR), it is the neuronal receptor for the myelin- associated proteins Nogo-A, OMgp (oligodendrocyte myelin glycoprotein), and MAG (myelin-associated glycoprotein) and mediates the inhibition of CNS axonal regeneration ...

重组蛋白

Nogo Receptor/RTN4R Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01200

Species: Cynomolgus

Expression System: HEK293 Cells

NgR Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00295

Species: Mouse

Expression System: HEK293 Cells

NgR3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00277

Species: Human

Expression System: HEK293 Cells

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